Chalkones: reactivity of aryl o-alkoxystyryl ketone dibromides and the synthesis of flavones therefrom

Bhagwat, N. A. ; Wheeler, T. S. (1939) Chalkones: reactivity of aryl o-alkoxystyryl ketone dibromides and the synthesis of flavones therefrom Journal of the Chemical Society . pp. 94-96. ISSN 0368-1769

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Official URL: http://pubs.rsc.org/en/content/articlelanding/1939...

Related URL: http://dx.doi.org/10.1039/JR9390000094

Abstract

Aryl β : 2-dialkoxystyryl ketones(II), which are readily obtained from the corresponding chalkone dibromides, yield flavones on treatment with hydrogen bromide in acetic acid. These dibromides undergo many of the reactions already described for aryl p- alkoxystyryl ketone dibomides (J., 1937, 1798); in both the o- and the p-alkoxystyryl dibromides, the side-chain halogen atom adjacent to the nucleus containing the alkoxy- group is replaced by alkoxyl on treatment with alcohols.

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