Siddique, A. K. ; Nair, G. B. ; Alam, M. ; Sack, D. A. ; Huq, A. ; Nizam, A. ; Longini Jr, I. M. ; Qadri, F. ; Faruque, S. M. ; Colwell, R. R. ; Ahmed, S. ; Iqbal, A. ; Bhuiyan, N. A. ; Sack, R. B. (2010) El Tor cholera with severe disease: a new threat to Asia and beyond Epidemiology and Infection, 138 (3). pp. 347-352. ISSN 0950-2688
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Official URL: http://journals.cambridge.org/action/displayAbstra...
Related URL: http://dx.doi.org/10.1017/S0950268809990550
Abstract
During epidemics of cholera in two rural sites (Bakerganj and Mathbaria), a much higher proportion of patients came for treatment with severe dehydration than was seen in previous years. V. cholerae O1 isolated from these patients was found to be El Tor in its phenotype, but its cholera toxin (CT) was determined to be that of classical biotype. Whether the observed higher proportion of severe dehydration produced by the El Tor biotype was due to a shift from El Tor to classical CT or due to other factors is not clear. However, if cholera due to strains with increased severity spread to other areas where treatment facilities are limited, there are likely to be many more cholera deaths.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Cambridge University Press. |
| Keywords: | Cholera; El Tor Toxin; Epidemic; Severe Dehydration; Vibrio Cholerae |
| ID Code: | 80572 |
| Deposited On: | 01 Feb 2012 13:00 |
| Last Modified: | 01 Feb 2012 13:00 |
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