HLA, complement C2, C4, properdin factor B and glyoxalase types in South Indian diabetics

Kirk, R. L. ; Ranford, P. R. ; Serjeantson, S. W. ; Thompson, A. R. ; Munirathnam Chetty, S. M. ; John, Lily ; Mohan, V. ; Ramachandran, A. ; Snehalatha, C. ; Viswanathan, M. (1985) HLA, complement C2, C4, properdin factor B and glyoxalase types in South Indian diabetics Diabetes Research and Clinical Practice, 1 (1). pp. 41-47. ISSN 0168-8227

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0168-8227(85)80027-9

Abstract

A series of diabetic patients from 3 centres in South India have been tested for HLA A, HLA B, BF, C2, C4A, C4B and GLO types. For insulin-dependent diabetes mellitus (IDDM) patients there was a significant increase in HLA B8, of BF F and decrease of C4 A6. No significant variation in HLA, BF, C2 or GLO frequencies was found in non-insulin-dependent diabetes mellitus (NIDDM) patients, but there was a significant decrease in C4B 1 and an increase in C4B 2. The HLA and BF association in South Indian IDDM patients is very different from that reported previously in North India.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Insulin-dependent Diabetes Mellitus; Non-insulin-dependent Diabetes Mellitus; South India; Chromosome 6 Markers; HLA; BF; C2; C4A; C4B
ID Code:80535
Deposited On:01 Feb 2012 09:27
Last Modified:01 Feb 2012 09:27

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