Pancreatic B-cell function in relation to diabetic retinopathy in Asian Indian NIDDM patients

Snehalatha, Chamukuttan ; Mohan, Rema ; Mohan, Viswanathan ; Ramachandran, Ambady ; Viswanathan, Moopil (1988) Pancreatic B-cell function in relation to diabetic retinopathy in Asian Indian NIDDM patients Acta Diabetologica, 25 (2). pp. 95-100. ISSN 0940-5429

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Official URL: http://www.springerlink.com/content/g587211768g663...

Related URL: http://dx.doi.org/10.1007/BF02581372

Abstract

Pancreatic B-cell function in relation to diabetic retinopathy was studied in 195 NIDDM patients with long-standing diabetes. Background diabetic retinopathy (BDR) was present in 95 (48.7%) and proliferative retinopathy (PDR) in 17 (8.7%) of the subjects. There was no significant difference between the BDR, PDR, and non-retinopathy groups with respect to age, age at diagnosis of diabetes and HbA1 values. Mean duration of diabetes was higher in the PDR group (p<0.05). Serum C-peptide values showed no correlation with the presence of retinopathy or with the duration of diabetes. The C-peptide values were widely scattered in patients with BDR and PDR showing no association between pancreatic B-cell reserve and occurrence or severity of retinopathy in NIDDM patients. Thus, decreased pancreatic B-cell reserve does not appear to be a risk factor for diabetic retinopathy in NIDDM patients.

Item Type:Article
Source:Copyright of this article belongs to Springer.
Keywords:B-cell Function; Diabetic Retinopathy; Microvascular Complications; Serum C-peptide
ID Code:80502
Deposited On:01 Feb 2012 09:38
Last Modified:01 Feb 2012 09:38

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