Exocrine pancreatic functions in tropical fibrocalculous pancreatic diabetes

Mohan, V. ; Snehalatha, C. ; Ahmed, M. R. ; Madanagopalan, N. ; Chari, S. ; Jayanthi, V. ; Malathi, S. ; Ramachandran, A. ; Viswanathan, M. (1989) Exocrine pancreatic functions in tropical fibrocalculous pancreatic diabetes Diabetes Care, 12 (2). pp. 145-147. ISSN 0149-5992

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Exocrine pancreatic function was studied by fecal chymotrypsin test in three groups of diabetic patients seen in southern India. Exocrine pancreatic insufficiency, as shown by low fecal chymotrypsin levels, was seen in 87.5% of patients with fibrocalculous pancreatic diabetes (FCPD), in 23.5% of insulin-dependent diabetes mellitus patients, and in 4.5% of non-insulin-dependent diabetes mellitus patients. There was no correlation between fecal chymotrypsin levels and serum amylase, serum lipase, age, body mass index, duration of diabetes, fasting plasma glucose, or glycosylated hemoglobin levels. The fecal chymotrypsin test is a useful additional investigation for the diagnosis of FCPD found in tropical countries.

Item Type:Article
Source:Copyright of this article belongs to American Diabetes Association.
ID Code:80492
Deposited On:01 Feb 2012 09:39
Last Modified:01 Feb 2012 09:39

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