Effect of cassava on motor co-ordination and neurotransmitter level in the albino frat

Mathangi, D. C. ; Mohana, V. ; Namasivayam, A. (1999) Effect of cassava on motor co-ordination and neurotransmitter level in the albino frat Food and Chemical Toxicology, 37 (1). pp. 57-60. ISSN 0278-6915

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0278-6915(98)00099-4

Abstract

The root of Cassava, a tropical plant, is consumed in the tropics and has been attributed as the cause for various tropical neuropathies. This study aims to discover the neurotoxic effects of chronic cassava consumption of Indian origin and the effect of malnutrition. The assessment is based on the motor co-ordination and brain neurotransmitters in rats. Cassava consumption reduced the motor co-ordination, but the changes in neurotransmitter levels due to cassava consumption (except for 5HT in corpus striatum) was identical with malnutrition-induced changes, indicating that the toxicity of chronic cassava consumption (of Indian origin) is mainly due to the associated protein calorie malnutrition (PCM).

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Cassava; l-dopa; Dopamine; 5-hydroxy Tryptamine; 5-hydroxy Indole Acetic Acid; Homovanillic Acid
ID Code:80266
Deposited On:31 Jan 2012 10:15
Last Modified:31 Jan 2012 10:15

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