Outcome in juvenile rheumatoid arthritis in India

Aggarwal, Amita ; Agarwal, Vikas ; Danda, Debasish ; Misra, Ramnath (2004) Outcome in juvenile rheumatoid arthritis in India Indian Pediatrics, 41 . pp. 180-184. ISSN 0019-6061

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Official URL: http://media.kenanaonline.com/files/0017/17780/180...


Juvenile rheumatoid arthritis (JRA) leads to significant morbidity due to continued disease activity and drug toxicity. Retrospective analysis of patients with JRA seen at a tertiary care hospital between 1990-2000 was done. Data regarding the type of onset, course of disease, joints involved, treatment received, drug toxicity and outcome at last visit were retrived from case records. There were 214 children (76 oligoarticular, 93 polyarticular and 45 systemic onset) with 135 of them being boys. At last followup, with median disease duration of 6 years; 128 had active disease, 58 had stable disease and 28 had inactive disease. Polyarticular group had the worst outcome with only 3 of the 93 having inactive disease (13/76 in oligo articular group and 12/45 in systemic onset disease). Intramuscular gold and D-Penicillamine were associated with significant drug toxicity. Outcome of children with JRA in our country is poorer as compared to developed countries.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Pediatrics.
Keywords:Juvenile Rheumatoid Arthritis, DMARD
ID Code:79473
Deposited On:27 Jan 2012 13:19
Last Modified:27 Jan 2012 13:19

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