Biomimetic studies on anti-thyroid drugs and thyroid hormone synthesis

Roy, Gouriprasanna ; Nethaji, Munirathinam ; Mugesh, G. (2004) Biomimetic studies on anti-thyroid drugs and thyroid hormone synthesis Journal of the American Chemical Society, 126 (9). pp. 2712-2713. ISSN 0002-7863

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ja039860g

Related URL: http://dx.doi.org/10.1021/ja039860g

Abstract

The selenium analogues of anti-thyroid drugs exhibit their anti-thyroid action by a mechanism different from that of MMI. The selenium analogue of MMI and related selenium compounds exhibit high GPx activity, providing a novel method for the reversible inhibition of thyroid hormone biosynthesis.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:79336
Deposited On:25 Jan 2012 06:05
Last Modified:25 Jan 2012 06:05

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