Studies directed towards the synthesis of immunosuppressive agent FK-506: synthesis of the entire bottom-half

Rama Rao, A. V. ; Chakraborty, T. K. ; Laxma Reddy, K. (1991) Studies directed towards the synthesis of immunosuppressive agent FK-506: synthesis of the entire bottom-half Tetrahedron Letters, 32 (9). pp. 1251-1254. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)92058-6

Abstract

Stereoselective addition of the chiral Grignard reagent derived from C16 bromide to C15 aldehyde paved the way for an efficient synthesis of the entire BOTTOM-HALF of FK-506.

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ID Code:78263
Deposited On:18 Jan 2012 12:14
Last Modified:23 Jun 2012 09:46

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