In vitro effect of inhibin on cyclic AMP dependent phosphodiesterase activity in rat testis

Sheth, Anil R. ; Vijayalakshmi, S. ; Sheth, Parul R. ; Bandivdekar, A. H. ; Moodbidri, Sudhir B. (1982) In vitro effect of inhibin on cyclic AMP dependent phosphodiesterase activity in rat testis Journal of Andrology, 3 (1). pp. 69-71. ISSN 0196-3635

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Abstract

We have previously reported that incubation of testicular slices with inhibin in the presence of 6 × 10-8 M oFSH resulted in a dose-related reduction in accumulation of cyclic AMP due to a decrease in adenyl cyclase activity. The present study demonstrates that inhibin enhances the cyclic AMP-phosphodiesterase activity in rat testicular tissue. These results suggest an additional mechanism by which cyclic AMP levels in gonadal tissue could be regulated by inhibin.

Item Type:Article
Source:Copyright of this article belongs to American Society of Andrology.
Keywords:Inhibin; Cyclic AMP-phosphodiesterase
ID Code:78206
Deposited On:18 Jan 2012 07:00
Last Modified:18 Jan 2012 07:00

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