Fate of Fluoride following its administration into a Biological system - an in vivo study

Abstract

Although it is established that excessive ingestion of fluoride leads to its deposition in tissues, it is not fully understood how much of it is deposited, hnw murh in i-xcrered and whdi quantity of fluoride is in circulation. Uhether the rate of uptake and retention of fluoride is the same or different with regard to different tissues is not known. Some of these questions have been answered by conducting a survey on fluoride content in tissues of various organs of rabbits namely, calcified tissues, noncalcified tissues, serum and urine after ingestion of 10 rag NaF daily for varying periods of time.