Modulation of rat prostatic inhibinlike peptide (PIP) by steroids and protein hormones

Teni, T. R. ; Sheth, A. R. ; Sheth, N. A. (1988) Modulation of rat prostatic inhibinlike peptide (PIP) by steroids and protein hormones Systems Biology in Reproductive Medicine, 20 (3). pp. 211-217. ISSN 1939-6368

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Official URL: http://informahealthcare.com/doi/abs/10.3109/01485...

Related URL: http://dx.doi.org/10.3109/01485018808987075

Abstract

Prostatic inhibinlike peptide (PIP) was detected in the ventral but not in the dorsal lobe of rat prostate. On orchiectomy, PIP concentration in the ventral prostate increased significantly, whereas it decreased on testosterone administration and attained value comparable with that in intact control. Estradiol-17β-treated animals exhibited high levels of PIP in absence of significant alterations in the protein content. The effect of prolactin and human chorionic gonadotropin on PIP concentration was not so prominent at the dose levels studied. The present study thus demonstrates negative regulation of PIP by testosterone and stimulatory effect of estradiol-170 on PIP in rat ventral prostrate.

Item Type:Article
Source:Copyright of this article belongs to Informa plc.
Keywords:Prostatic Inhibinlike Peptide; Rat Prostrate; Ventral Prostrate; Testoterone; Estradiol-17β
ID Code:78080
Deposited On:17 Jan 2012 09:41
Last Modified:17 Jan 2012 09:41

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