Effect of FSH deprivation on spermatogenesis in prepubertal mice

Nandedkar, T. D. ; Sarvamangala, B. S. ; Raghavan, V. P. ; Sheth, A. R. (1982) Effect of FSH deprivation on spermatogenesis in prepubertal mice Systems Biology in Reproductive Medicine, 8 (4). pp. 257-260. ISSN 1939-6368

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Official URL: http://informahealthcare.com/doi/abs/10.3109/01485...

Related URL: http://dx.doi.org/10.3109/01485018208990206


A specific antiserum to ovine follicle stimulating hormone (AS/FSH) raised in rabbits and administered to prepubertal mice from days 5 to 35 of age, inhibited intermediate and type B spermatogonia. Development of spermatocytes, spermatids, and spermatozoa was affected, indicating a role for FSH in the initiation of spermatogenesis. Decrease in the testicular and epididymal weights, but not that of seminal vesicles and ventral prostate, demonstrated the specific action of AS/FSH. Reduction in the weights of the epididymis in AS/FSH-injected mice accompanied by the absence of spermatozoa in the lumen suggests a possible role for FSH in spermiation.

Item Type:Article
Source:Copyright of this article belongs to Informa plc.
Keywords:FSH; Spermatogenesis; Sertoli Cell; Spermiation
ID Code:78076
Deposited On:17 Jan 2012 09:41
Last Modified:17 Jan 2012 09:41

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