Isolation and characterization of ovine testicular and ovarian inhibin

Vijayalakshmi, S. ; Bandivdekar, A. H. ; Joshi, Lata R. ; Moddbidri, S. B. ; Sheth, A. R. (1980) Isolation and characterization of ovine testicular and ovarian inhibin Systems Biology in Reproductive Medicine, 5 (2). pp. 179-188. ISSN 1939-6368

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Official URL: http://informahealthcare.com/doi/abs/10.3109/01485...

Related URL: http://dx.doi.org/10.3109/01485018008986313

Abstract

Low-molecular-weight (7<1500 daltons) peptides with inhibin activity have been isolated from sheep testes and ovaries by simple gel filtration. These peptides were capable of inhibiting the ovarian weight increase in hCG-primed immature female mice and also of suppressing the post-castration rise of serum FSH levels in adult male rats, suggesting similarities in their biological properties. Both testicular and ovarian inhibin were trypsin sensitive and heat stable at 100°C for 30 min and were shown to act by interfering with the production of a hypothetical FSH-RH.

Item Type:Article
Source:Copyright of this article belongs to Informa plc.
Keywords:Inhibin; Testis; Ovary; Sheep
ID Code:78070
Deposited On:17 Jan 2012 09:39
Last Modified:17 Jan 2012 09:39

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