Local anti-fertillity effect of inhibin-enriched preparation (IEP) in female hamsters

Bapat, B. V. ; Nandedkar, T. D. ; Sheth, A. R. (1984) Local anti-fertillity effect of inhibin-enriched preparation (IEP) in female hamsters Contraception, 29 (4). pp. 367-374. ISSN 0010-7824

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0010-7824(84)90070-2

Abstract

An inhibin-enriched preparation (IEP) involved in the regulation of follicle stimulating hormone (FSH) is known to play an important role in the normal ovarian cycle. In utero administration of 10 μg of IEP on day 3 of pregnancy completely prevented implantation in hamsters. No toxic effect of IEP was observed on the blastocysts as indicated by the dye exclusion test performed with Trypan blue. Thus, the results of the present study indicate an extra-pituitary site of action for the anti-implantation effect of IEP.

Item Type:Article
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ID Code:78061
Deposited On:17 Jan 2012 09:41
Last Modified:17 Jan 2012 09:41

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