Rastogi, A. ; Singh, V. K. ; Biswas, S. ; Haq, W. ; Mathur, K. B. ; Agarwal, S. S. (1993) Augmentation of human natural killer cells by splenopentin analogs FEBS Letters, 317 (1-2). pp. 93-95. ISSN 0014-5793
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001457...
Related URL: http://dx.doi.org/10.1016/0014-5793(93)81498-O
Abstract
Splenopentin, Arg-Lys-Glu-Val-Tyr (SP-5) and its synthetic analogs; Arg-d-Lys-Glu-Val-Tyr (pentapeptide ), Lys-Lys-Glu-Val-Tyr , d-Lys-Lys-Glu-Val-Tyr , Arg-Lys-Gly-Val-Tyr, and Arg-Lys-Gln-Val-Tyr have been examined for augmentation of human natural killer (NK) cell activity and human T-cell transformation response. Pentapeptides 2 and 3 were found to significantly augment the in vitro human NK cell activity. However, none of them had any effect on lymphocyte proliferative responses.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Federation of European Biochemical Societies. |
| Keywords: | Splenopentin; Thymopoietin; NK Cell Cytotoxicity; T-cell Transformation; Immunomodulator |
| ID Code: | 78 |
| Deposited On: | 16 Sep 2010 10:50 |
| Last Modified: | 16 May 2016 11:21 |
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