Synthesis of Cairomycin-B, a novel biocyclic peptide containing Lysine and aspartic acid

Kumar, A. ; Singh, M. ; Chauhan, V. S. (1986) Synthesis of Cairomycin-B, a novel biocyclic peptide containing Lysine and aspartic acid Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry, 25 . pp. 230-232. ISSN 0376-4699

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Abstract

Cairomycin-B, a bicyclic peptide antibiotic containing lysine and aspartic acid has been synthesised. Diketopiperazine first prepared from compound (3), deprotected and subjected to internal cyclisation using DCC and N-hydroxysuccinimid to yield the title compound (7) in 11% yield. All the intermediates and final compound have been fully characterised.

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Deposited On:12 Jan 2012 14:37
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