Nature of newly synthesized RNA in developing rat brain

Singh, U. N. (1965) Nature of newly synthesized RNA in developing rat brain Canadian Journal of Biochemistry, 43 (7). pp. 1083-1089. ISSN 0008-4018

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Sedimentation characteristics of labelled RNA synthesized in young rat brain slices have been studied by sucrose density gradient centrifugation. A major fraction of the radioactivity derived from adenine-8-C14 in phenol-extractable RNA is shown to be localized in soluble RNA and in relatively small amounts of highly labile fractions in the region lying between 10 S and 20 S. Smaller peaks with S values greater than 30 are also observed. The radioactivity profile of a rapidly labelled RNA isolated from interphase is found to be in sharp contrast with that of phenol-extractable RNA.

Item Type:Article
Source:Copyright of this article belongs to NRC Research Press.
ID Code:77292
Deposited On:11 Jan 2012 04:25
Last Modified:11 Jan 2012 04:25

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