Chemical approaches to the re-structuring of proteins

Ranganathan, S. ; Ranganathan, D. ; Bamezai, S. ; Singh, W. P. ; Bhattacharyya, D. ; Singh, G. P. ; Rathi, R. ; Saini, S. ; Jayaraman, N. ; Patel, B. K. (1990) Chemical approaches to the re-structuring of proteins Pure and Applied Chemistry, 62 (7). pp. 1437-1440. ISSN 0033-4545

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Methodologies for protein re-structuring have been developed enabling site specific side chain modification to either coded or non-coded residues. Procedures for the modification of the protein profile by attachment of either pendants or structural motifs have been delineated. Selectivity has been demonstrated on the basis of modulation of the -CH2- spacer, which interposes the functional group and the peptide backbone.

Item Type:Article
Source:Copyright of this article belongs to International Union of Pure and Applied Chemistry.
ID Code:76839
Deposited On:07 Jan 2012 08:45
Last Modified:18 May 2016 20:22

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