Eicosapentapeptide repeats (EPRs): novel repeat proteins specific to flowering plants

Archak, Sunil ; Nagaraju, Javaregowda (2006) Eicosapentapeptide repeats (EPRs): novel repeat proteins specific to flowering plants Bioinformatics, 22 (20). pp. 2455-2458. ISSN 1367-4803

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Official URL: http://bioinformatics.oxfordjournals.org/content/2...

Related URL: http://dx.doi.org/10.1093/bioinformatics/btl340

Abstract

In this report, we describe a novel tandem peptide repeat protein, Eicosapentapeptide repeat (EPR), which occurs notably only in flowering plants. The EPRs are characterized by a 25 amino acid repeat unit, X2CX4CX10CX2HGGG, repeated 10 times tandemly. Sequence search revealed that the repeat motif is highly conserved across its occurrence. EPRs are predicted to exist as quasi-globular stable structures owing to highly conserved amino acid positions and potential disulfide bridges. Proteins containing EPRs are predicted to be located in chloroplasts; non-enzymatic and peptide or DNA-binding in molecular function; and they are possibly involved in transcription regulation.

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Deposited On:05 Jan 2012 06:22
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