Singh, Yogendra ; Chaudhary, V. K. ; Tyagi, S. R. ; Misra, U. K. (1983) Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats Toxicology Letters, 20 (2). pp. 219-223. ISSN 0378-4274
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0378-4274(84)90150-4
Abstract
Rats maintained on a 20% casein diet were given malathion orally throughout the feeding period (100 mg/kg body weight/day, dissolved in groundnut oil). Hepatic choline kinase (EC 2.7.1.32) and cholinephosphate cytidyltransferase (EC 2.7.7.15) activities were inhibited, whereas cholinephosphotransferase (EC 2.7.8.2) activity was not affected by malathion administration. Incorporation of [methyl-14C]L-methionine into hepatic microsomal phosphatidylcholine was significantly reduced by malathion administration.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 74272 |
| Deposited On: | 09 Dec 2011 05:30 |
| Last Modified: | 09 Dec 2011 05:30 |
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