Hepatic phosphatidylcholine synthesis in deficiency of lysine and threonine: effect of Malathion

Singh, Y. ; Chaudhary, V. K. ; Tyagi, S. R. ; Bhatnagar, R. ; Misra, U. K. (1988) Hepatic phosphatidylcholine synthesis in deficiency of lysine and threonine: effect of Malathion Cellular and Molecular Life Sciences, 44 (9). pp. 758-759. ISSN 1420-682X

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Official URL: http://www.springerlink.com/content/u6546r60n20155...

Related URL: http://dx.doi.org/10.1007/BF01959153

Abstract

Rats fed on a rice diet deficient in lysine and threonine showed increased activities of CDP-Choline pathway enzymes and incorporation of (methyl-3H)-choline into hepatic microsomal phosphatidylcholine, compared to rats fed on the same diet supplemented with lysine and threonine. However, the amount of microsomal phosphatidylcholine was significantly decreased in rats fed a deficient rice diet. These results suggest an enhanced phosphatidylcholine catabolism in rats fed on a rice diet deficient in lysine and threonine. Malathion administration reduced the amount of phosphatidylcholine in all the groups.

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