Molecular effects of uptake of gold nanoparticles in HeLa cells

Khan, Jameel Ahmad ; Pillai, Beena ; Das, Taposh Kumar ; Singh, Yogendra ; Maiti, Souvik (2007) Molecular effects of uptake of gold nanoparticles in HeLa cells ChemBioChem, 8 (11). pp. 1237-1240. ISSN 1439-4227

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/cbic.20...

Related URL: http://dx.doi.org/10.1002/cbic.200700165

Abstract

Mellow gold: Toxicogenomics of nanoparticles can expose subtle yet clinically relevant alterations in the intracellular environment that arise from downstream effects of nanoparticle accumulation inside cells. Genome-wide expression profiling by using DNA microarrays revealed that internalization of gold nanoparticles is not associated with gross changes in transcription in HeLa cells.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Cytotoxicity; Gene Expression; Microarrays; Nanostructures; Toxicogenomics
ID Code:74238
Deposited On:09 Dec 2011 05:35
Last Modified:09 Dec 2011 05:35

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