Innate metabolic differences and mutagen sensitivity of Drosophila melanogaster: I. Radiosensitivity of hyperkinetic mutant

Sharma, R. P. ; Chopra, V. L. (1975) Innate metabolic differences and mutagen sensitivity of Drosophila melanogaster: I. Radiosensitivity of hyperkinetic mutant Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis, 30 (1). pp. 77-82. ISSN 1386-1964

Full text not available from this repository.

Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0027-5107(75)90255-9

Abstract

The sensitivity to gamma-rays of a hyperkinetic mutant (HK1), characterized by high metabolic activity, has been studied and compared with gamma-ray sensitivity of the wild-type Oregon-K. Radiation damage, as measured by the frequency of induced dominant lethals (DL) and sex-linked recessive lethals (SLRL), was more in HK1 as compared with Or-K. The maximal sensitivity differences for these parameters were observed in the first brood. Translocations, on the contrary, were in general fewer in the HK1 compared with Or-K. These results have been interpreted in terms of reduced repair of mutational lesions in the energy-stressed cells of HK1.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:74059
Deposited On:08 Dec 2011 12:15
Last Modified:13 Jul 2012 14:45

Repository Staff Only: item control page