Variation at 4 short tandem repeat loci in 8 population groups of India

Mukherjee, N. ; Majumder, P. P. ; Roy, B. ; Roy, M. ; Dey, B. ; Chakraborty, M. ; Banerjee, S. (1999) Variation at 4 short tandem repeat loci in 8 population groups of India Human Biology, 71 (3). pp. 439-446. ISSN 0018-7143

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Abstract

We have determined the nature and extent of variation at 4 STR loci (CSF1P0, TPOX, TH01, VWA) in 8 caste and tribal population groups of eastern and northern India. Large differences in allele frequencies among the groups were found. Average heterozygosities in all populations were high (approximately 80%). The overall extent of gene differentiation among the 8 groups was high (GST = 0.04). The nature of genomic affinities based on these 4 STR loci does not completely agree with our earlier finding based on classical genetic markers that geographic proximity of habitat has a greater influence on genetic similarity between populations than sociocultural proximity does.

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