Nath, S. K. ; Majumder, P. P. ; Sarkar, S. (1992) Rh segregation distortion: an Artifact of ascertainment bias? The American Journal of Human Genetics, 50 (6). pp. 1328-1332. ISSN 0002-9297
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Abstract
On the basis of Rh blood group data on mother-child pairs collected from the maternity clinic of a hospital in Chile, Valenzuela and Harb postulated that there is a significant segregation distortion at the Rh locus. For data collected from a hospital, biases of ascertainment cannot be ruled out. For the Rh blood group locus, there is a strong possibility of preferential admission of Rh(−) pregnant women, especially of those Rh(−) women with Rh(+) husbands. We show that the evidence of segregation distortion vanishes when the possibility of such preferential admissions are taken into account.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Society of Human Genetics. |
| ID Code: | 73267 |
| Deposited On: | 03 Dec 2011 12:11 |
| Last Modified: | 03 Dec 2011 12:11 |
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