Facile entry into triazole fused heterocycles via sulfamidate derived azido-alkynes

Sudhir, V. Sai ; Phani Kumar, N. Y. ; Baig, R. B. Nasir ; Chandrasekaran, Srinivasan (2009) Facile entry into triazole fused heterocycles via sulfamidate derived azido-alkynes Journal of Organic Chemistry, 74 (19). pp. 7588-7591. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo9016748

Related URL: http://dx.doi.org/10.1021/jo9016748

Abstract

Direct synthesis of condensed triazoles from diverse sulfamidates by ring opening of sulfamidates with sodium azide followed by one-pot propargylation and cycloaddition furnished title compounds. The methodology in general has been demonstrated on diverse sulfamidates derived from amino acids, amino acid derivatives, and carbohydrates to obtain diverse triazole fused scaffolds. In one example, a condensed triazole containing amino acid has been synthesized by ring opening of a sulfamidate derivative with propargyl amine.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:7243
Deposited On:25 Oct 2010 12:03
Last Modified:01 Feb 2011 09:03

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