Butyrate-induced alteration in lipid composition of human colon cell line HT-29

Madesh, M. ; Bernard, O. ; Balasubramanian, K. A. (1996) Butyrate-induced alteration in lipid composition of human colon cell line HT-29 Biochemistry & Molecular Biology International, 38 (4). pp. 659-664. ISSN 1039-9712

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Abstract

The effect of butyrate-induced differentiation on lipid composition of HT-29 cells were studied. It was observed that cell differentiation was associated with increased activity of alkaline phosphatase and changes in the lipid composition. Differentiated cells showed increased level of triacylglycerol, cholesteryl esters and decreased free cholesterol and phospholipids. Changes were also observed in individual phospholipid composition. It appears that butyrate induced differentiation is associated with increased esterification of neutral lipids.

Item Type:Article
Source:Copyright of this article belongs to International Union of Biochemistry and Molecular Biology.
ID Code:72202
Deposited On:28 Nov 2011 06:35
Last Modified:28 Nov 2011 06:35

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