Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei

Majumder, Hemanta K. ; Boothroyd, John C. ; Weber, Hans (1981) Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei Nucleic Acids Research, 9 (18). pp. 4745-4753. ISSN 0305-1048

Full text not available from this repository.

Official URL: http://nar.oxfordjournals.org/content/9/18/4745.sh...

Related URL: http://dx.doi.org/10.1093/nar/9.18.4745

Abstract

Sequences corresponding to the complete 3'-terminal regions of the messenger RNAs for three different Variant Surface Glycoproteins of Trypanosoma brucei were determined on complementary DNA inserts cloned in recombinant plasmids. The three sequences show 80-130 base pair long segments of strong (70-80%) homology at the 3' ends, whereas the regions upstream from the last 130-140 base pairs contain no significant homology. The signal AAUAAA, present near the 3' ends of almost all known polyadenylated mRNAs of eukaryotes, does not occur in the 3'-terminal sequences of these three variants.

Item Type:Article
Source:Copyright of this article belongs to Oxford University Press.
ID Code:72074
Deposited On:28 Nov 2011 05:28
Last Modified:28 Nov 2011 05:28

Repository Staff Only: item control page