Synthesis and applications of propargyl pentafluorophenyl carbonate for peptide synthesis

Bhat, Ramakrishna G. ; Kerouredan, Erwan ; Porhiel, Emmanuel ; Chandrasekaran, Srinivasan (2002) Synthesis and applications of propargyl pentafluorophenyl carbonate for peptide synthesis Tetrahedron Letters, 43 (13). pp. 2467-2469. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(02)00287-3

Abstract

Propargyl pentafluorophenyl carbonate was synthesised in quantitative yield by the reaction of propargyl chloroformate and pentafluorophenol. All the N-propargyloxycarbonyl (N-Poc) amino acids were obtained in good yield. The use of Poc-OPfp in peptide synthesis has been explored.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Amino Acids; Peptide Synthesis; Protecting Groups; Propargyl Pentafluorophenyl Carbonate; Tetrathiomolybdate
ID Code:7200
Deposited On:25 Oct 2010 12:12
Last Modified:01 Feb 2011 10:53

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