Short-course of oral miltefosine for treatment of visceral leishmaniasis

Sundar, Shyam ; Makharia, Anand ; More, Deepak K. ; Agrawal, Gaurav ; Voss, Andreas ; Fischer, Christina ; Bachmann, Peter ; Murray, Henry W. (2000) Short-course of oral miltefosine for treatment of visceral leishmaniasis Clinical Infectious Diseases, 31 (4). pp. 1110-1113. ISSN 1058-4838

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Official URL: http://cid.oxfordjournals.org/content/31/4/1110.ab...

Related URL: http://dx.doi.org/10.1086/318122

Abstract

A total of 54 Indian patients with visceral leishmaniasis were treated with oral miltefosine, 50 mg given twice daily, for 14 days (18 patients; group A), 21 days (18; group B), or 28 days (18; group C). Cure was achieved in 89% of group A, 100% of group B, and 100% of group C. Adverse reactions were self-limited and primarily mild. The 21-day miltefosine regimen combines high-level efficacy, convenient dosing, and a relatively short duration.

Item Type:Article
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ID Code:71760
Deposited On:28 Nov 2011 04:34
Last Modified:28 Nov 2011 04:34

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