Two-dimensional nuclear Overhauser effect experiment in a protein: the first NOESY (1979-80)

Anil Kumar, (2003) Two-dimensional nuclear Overhauser effect experiment in a protein: the first NOESY (1979-80) Magnetic Resonance in Chemistry, 41 (S1). S26-S32. ISSN 0749-1581

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Official URL: http://www3.interscience.wiley.com/journal/1055587...

Related URL: http://dx.doi.org/10.1002/mrc.1237

Abstract

The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a seminal development in the algorithm of protein structure determination by liquid-state NMR. This article provides a historical and personal view of the various facilities, challenges and solutions in the successful development of this experiment for biomolecules in Professor Wuthrich's laboratory during the academic year 1979-80.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons, Inc.
Keywords:Two-dimensional NMR; NOESY; COSY; Proton-proton NOE; Proteins; Biomolecules; Secondary Structure; Three-dimensional Structure; Liquid-state NMR
ID Code:712
Deposited On:25 Sep 2010 05:03
Last Modified:12 May 2011 08:41

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