Dharmalingam, K. ; Jayaraman, J. (1971) Mechanism of glucose repression of mitochondriogenesis: induction of phospholipases Biochemical and Biophysical Research Communications, 45 (5). pp. 1115-1118. ISSN 0006-291X
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0006-291X(71)90134-3
It has been demonstrated that in yeast (Saccharomyces cerevisiae), concomitant with the breakdown of mitochondrial membrane due to glucose repression, there is an increase in the level of phospholipase D activity. It is suggested that glucose induces the phospholipase D and this hydrolytic enzyme acts on the mitochondrial membrane and disintegrates it.
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