Chakraborty, T. K. ; Suresh, V. R. (1998) Synthetic studies toward potent cytotoxic agents amphidinolides: synthesis of the C1-C18 moiety of amphidinolides G, H and L Tetrahedron Letters, 39 (49). pp. 9109-9112. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0040-4039(98)02009-7
Abstract
Stereoselective synthesis of the (8S, 9S, 11R, 16S)-C1C18 segment 1 of amphidinolides G, H and L, bearing the unique trisubstituted “s-cis-1,3-diene” moiety (C28(29)C13C14C15), has been achieved for the first time following a highly efficient convergent strategy. A concise stereoselective synthesis of the C1C18 moiety 1 of amphidinolides G, H and L is described.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Amphidinolides; Antitumor Compounds; Macrolides; Asymmetric Alkylation |
| ID Code: | 69588 |
| Deposited On: | 14 Nov 2011 03:52 |
| Last Modified: | 14 Nov 2011 03:52 |
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