Components of seseli sibiricum: constitution and synthesis of sibiricin, a new coumarin

Austin, P. W. ; Seshadri, T. R. ; Sood, M. S. ; Vishwapaul, (1968) Components of seseli sibiricum: constitution and synthesis of sibiricin, a new coumarin Tetrahedron, 24 (8). pp. 3247-3253. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)92623-7

Abstract

From the pet. ether extract of S. sibiricum osthol, imperatorin, bergapten and a new coumarin named sibiricin have been isolated. It has been assigned 5,7-dimethoxy-coumarin-8-γ,γ-dimethylallyl epoxide structure on the basis of degradative and spectral studies. Final confirmation of the structure has been provided by a synthesis following an unambigous route using 3-dimethylallyl-2-hydroxy-4,6-dimethoxybenzaldehyde as the important intermediate.

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