The effect of nifedipine on exercise-induced asthma

Sharma, S. K. ; Pande, J. N. ; Guleria, J. S. (1986) The effect of nifedipine on exercise-induced asthma Journal of Asthma, 23 (1). pp. 15-17. ISSN 0277-0903

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This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA). Effect of sublingual administration of 20 mg of nifedipine or placebo was studied in randomized double-blind manner on separate days in 19 extrinsic asthmatic subjects. Nifedipine was found to be significantly effective in abolishing the exercise-induced decrease in forced vital capacity (FVC) and maximal expiratory flows (p < 0.001). There were no significant changes in heart rate and blood pressure after nifedipine.

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