The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

Terwilliger, T. C. ; Park, M. S. ; Waldo, G. S. ; Berendzen, J. ; Hung, L.-W. ; Kim, C.-Y. ; Smith, C. V. ; Sacchettini, J. C. ; Bellinzoni, M. ; Bossi, R. ; De Rossi, E. ; Mattevi, A. ; Milano, A. ; Riccardi, G. ; Rizzi, M. ; Roberts, M. M. ; Coker, A. R. ; Fossati, G. ; Mascagni, P. ; Coates, A. R. M. ; Wood, S. P. ; Goulding, C. W. ; Apostol, M. I. ; Anderson, D. H. ; Gill, H. S. ; Eisenberg, D. S. ; Taneja, B. ; Mande, S. ; Pohl, E. ; Lamzin, V. ; Tucker, P. ; Wilmanns, M. ; Colovos, C. ; Meyer-Klaucke, W. ; Munro, A. W. ; McLean, K. J. ; Marshall, K. R. ; Leys, D. ; Yang, J. K. ; Yoon, H.-J. ; Lee, B. I. ; Lee, M. G. ; Kwak, J. E. ; Han, B. W. ; Lee, J. Y. ; Baek, S.-H. ; Suh, S. W. ; Komen, M. M. ; Arcus, V. L. ; Baker, E. N. ; Lott, J. S. ; Jacobs, W. ; Alber, T. ; Rupp, B. (2003) The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology Tuberculosis, 83 (4). pp. 223-249. ISSN 1472-9792

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S1472-9792(03)00051-9

Abstract

The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Protein Structure; X-ray Crystallography; Structural Genomics; Mycobacterium Tuberculosis; Drug Discovery
ID Code:67371
Deposited On:29 Oct 2011 11:15
Last Modified:29 Oct 2011 11:15

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