Extra gonadal germ cell tumours: report of two cases

Kumar, Lalit ; Kumar, Sunesh ; Kamble, R. M. ; Sharma, Suash (1994) Extra gonadal germ cell tumours: report of two cases Journal of Obstetrics and Gynaecology, 20 (3). pp. 257-262. ISSN 0144-3615

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1447-...

Related URL: http://dx.doi.org/10.1111/j.1447-0756.1994.tb00466.x

Abstract

Extra gonadal germ cell tumours (EGGCT) in women are rare. We report here two such patients. The clinical and laboratory features were - young age, 25 and 22 years, midline location (mediastinum, scalp), elevated tumour marker and normal ovaries on CAT scan. The histological subtype was embryonal carcinoma in both cases. Complete response (CR) was achieved with cisplatin based chemotherapy (CT). Both patients had return of normal ovarian functions and have delivered normal babies (1st patient one, 2nd patient 2 babies). Both remain asymptomatic and disease-free at 30 + and 55 + months follow-up. We conclude that patients with EGGCT after treatment with cisplatin based CT achieve CR with return of normal ovarian functions and prolonged survival.

Item Type:Article
Source:Copyright of this article belongs to Informa plc.
Keywords:Germ Cell Tumor; Extra Gonadal Germ Cell Tumour; Cisplatin Based Chemotherapy
ID Code:66808
Deposited On:27 Oct 2011 06:26
Last Modified:27 Oct 2011 06:26

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