Gupta, Ajay ; Kumar, Lalit ; Karak, Ashok ; Thulkar, Sanjay ; Rastogi, Ruchi ; Bhatti, Sahibinder (2009) Multicentric hyaline-vascular type castleman disease presenting as an epidural mass causing paraplegia: a case report Clinical Lymphoma, Myeloma & Leukemia, 9 (3). pp. 250-253. ISSN 1557-9190
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Official URL: http://cigjournals.metapress.com/content/9n7r8kn9t...
Related URL: http://dx.doi.org/10.3816/CLM.2009.n.050
Abstract
A 30-year-old woman presented with a 1-year history of cervical lymph node enlargement and paraparesis of 2 weeks' duration. Magnetic resonance imaging revealed an epidural mass extending from the second to fifth thoracic levels causing compressive myelopathy. The cervical lymph node biopsy revealed hyaline vascular multicentric Castleman disease. She was given dexamethasone and radiation therapy to the involved spine followed by 8 cycles of CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy. The patient achieved complete remission and is disease free 24 months after treatment. The case is being reported in view of its rarity and achievement of complete remission with chemotherapy and radiation therapy.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to CIG Media Group, LP. |
| Keywords: | Castleman's Disease; CHOP; Complete Remission; Cyclophosphamide; Doxorubicin; Paraplegia Neurologic Involvement; Vincristine |
| ID Code: | 66805 |
| Deposited On: | 27 Oct 2011 06:42 |
| Last Modified: | 27 Oct 2011 06:42 |
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