Synthesis of novel quinone-amino acid hybrids via cross-enyne metathesis and Diels-Alder reaction as key steps

Kotha, Sambasivarao ; Mandal, Kalyaneswar ; Banerjee, Shaibal ; Mobin, Shaikh M. (2007) Synthesis of novel quinone-amino acid hybrids via cross-enyne metathesis and Diels-Alder reaction as key steps European Journal of Organic Chemistry, 2007 (8). pp. 1244-1255. ISSN 1434-193X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.20...

Related URL: http://dx.doi.org/10.1002/ejoc.200600970

Abstract

A "Building Block Approach" for the synthesis of various quinone-amino acid hybrids through ethylene cross-enyne metathesis and Diels-Alder reaction as key steps is described. A library of comformationally constrained quinone-based phenylalanine derivatives and dicarba analogs of cystine have been generated starting from a common precursor using Grubbs' catalysts. This methodology has also been extended for the synthesis of fullerene-based dicarba analogs of cystine.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Quinone-amino Acid Hybrids; Cross-enyne Metathesis; Cycloaddition; Fullerenes
ID Code:65193
Deposited On:15 Oct 2011 11:45
Last Modified:15 Oct 2011 11:45

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