Friedel-crafts approach to electron deficient cyclic α-amino acids

Kotha, Sambasivarao ; Anglos, Demetrios ; Kuki, Atsuo (1992) Friedel-crafts approach to electron deficient cyclic α-amino acids Tetrahedron Letters, 33 (12). pp. 1569-1572. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)91676-9

Abstract

An electron deficient 2,2-dimethyl-1-H-phenalene-1,3-dione based cyclic α-amino acid was synthesized in 7 steps using Friedel-Crafts acylation as the key step. A new recipe was found to deprotect the required phthalimide protecting group in highly hindered substrates.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Electron Deficient α-amino Acid; Friedel-Crafts Acylation
ID Code:65180
Deposited On:15 Oct 2011 09:39
Last Modified:15 Oct 2011 11:33

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