Effect of sodium fluoride — on erythrocyte membrane function — with reference to metal ion transport in rabbits

Jain, Suresh K. ; Susheela, A. K. (1987) Effect of sodium fluoride — on erythrocyte membrane function — with reference to metal ion transport in rabbits Chemosphere, 16 (5). pp. 1087-1094. ISSN 0045-6535

Full text not available from this repository.

Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0045-6535(87)90045-2

Abstract

Effect of NaF on membrane function was examined with reference to metal ion transport in rabbit's erythrocytes. Activities of membranal enzymes [Na+ + K+ - ATPase & Mg++ - ATPase], plasma enzymes [Acid and Alkaline Phosphatases] and concentrations of Ca, Mg, Na and K were estimated in erythrocyte membrane, hemolysate and plasma. A 17% decrease in Na+ + K+ - ATPase and 37% increase in Mg++ - ATPase have been observed after fluoride ingestion. Plasma, Acid and Alkaline Phosphatases are reduced by 27% and 34% respectively. Fluoride in circulation and in erythrocyte membrane do not effect the concentration of Na and K, however, Ca and Mg are significantly altered in erythrocyte membrane, hemolysate and plasma. It is concluded that fluoride is affecting the normal erythrocyte membrane function.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:64549
Deposited On:12 Oct 2011 05:00
Last Modified:12 Oct 2011 05:00

Repository Staff Only: item control page