An angular trinuclear copper(II) complex as a model for the active site of multicopper oxidases

Gupta, Sunita ; Mukherjee, Arindam ; Nethaji, Munirathinam ; Chakravarty, Akhil R. (2004) An angular trinuclear copper(II) complex as a model for the active site of multicopper oxidases Polyhedron, 23 (4). pp. 643-647. ISSN 0277-5387

Full text not available from this repository.

Official URL:

Related URL:


A new angular trinuclear copper(II) complex [Cu3L1L2(1-MeIm)(H2O)](ClO4) (1), where H3L1 and H2L2 are penta and tetra-dentate Schiff base ligands, is prepared from a reaction of [CuL2] and [Cu2L1(μ-Br)] in the presence of 1-methylimidazole (1-MeIm) and isolated as a perchlorate salt. The complex which crystallizes in the monoclinic space group P21/n shows the presence of a discrete angular trinuclear copper(II) core in which the monomeric precursor is linked with the dimeric precursor through phenoxo bridges. The core structure resembles well with the active site structure of blue multicopper oxidases. The Cu...Cu separations of ca. 3.3 Å in the angular unit is 0.4 Å shorter than those observed in the active site of the oxidized form of ascorbate oxidase. The complex displays a visible band at 620 nm (ε=500 M-1 cm-1) in DMSO. It shows magnetic moment values of 3.07 and 2.18 μB at 300 and 18 K, respectively, for the Cu3 cluster. The complex models the structural and magnetic properties of the trinuclear active site of blue copper oxidases. An angular copper(II) complex [Cu3L1L2(1-MeIm)(H2O)](ClO4) has been synthesized by reacting type-2 and type-3 mimic precursor complexes, where H3L1 and H2L2 are penta and tetradentate Schiff base ligands. The complex, characterized by X-ray diffraction, models the active site structural features and magnetic properties of blue copper oxidases.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Tricopper(II) complex; Schiff bases; Ascorbate oxidase model; Crystal structure; Magnetic properties
ID Code:6436
Deposited On:20 Oct 2010 10:24
Last Modified:27 May 2011 04:57

Repository Staff Only: item control page