ZrCl4 as a mild and efficient catalyst for the one-pot conversion of TBS and THP ethers to acetates

Sanjeeva Reddy, Ch. ; Smitha, G. ; Chandrasekhar, S. (2003) ZrCl4 as a mild and efficient catalyst for the one-pot conversion of TBS and THP ethers to acetates Tetrahedron Letters, 44 (25). pp. 4693-4695. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(03)01078-5

Abstract

A mild, efficient and chemoselective method has been developed for the direct transformation of tert-butyldimethylsilyl and tetrahydropyranyl protected alcohols into the corresponding acetates with acetic anhydride and zirconium(IV) chloride as the catalyst in acetonitrile, in a one-pot reaction with high yields and short reaction times. This method has been applied to a variety of substrates.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Zirconium(IV) Chloride; One-pot Reaction
ID Code:63481
Deposited On:29 Sep 2011 04:19
Last Modified:29 Sep 2011 04:19

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