CeCl3·7H2O/LiI: a novel reagent system for the synthesis of 4-iodotetrahydropyrans via prins cyclization

Yadav, J. S. ; Subba Reddy, B. V. ; Narayana Kumar, G. G. K. S. ; Madhusudhan Reddy, G. (2007) CeCl3·7H2O/LiI: a novel reagent system for the synthesis of 4-iodotetrahydropyrans via prins cyclization Chemistry Letters, 36 (3). pp. 426-427. ISSN 0366-7022

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Official URL: http://www.jstage.jst.go.jp/article/cl/36/3/36_426...

Related URL: http://dx.doi.org/10.1246/cl.2007.426

Abstract

Homoallylic alcohols undergo smooth coupling with a variety of aldehydes in the presence of CeCl3·7H2O-LiI reagent system in refluxing dichloroethane under neutral conditions to produce the corresponding 4-iodotetrahydropyran derivatives in high yields. The spirocyclic-4-iodotetrahydropyrans are obtained in case of cyclic ketones.

Item Type:Article
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ID Code:63206
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