First stereoeselective total synthesis of sporostatin and determination of absolute configuration

Yadav, J. S. ; Thrimurtulu, N. ; Uma Gayathri, K. ; Subba Reddy, B. V. ; Prasad, A. R. (2009) First stereoeselective total synthesis of sporostatin and determination of absolute configuration Synlett, 5 . pp. 790-792. ISSN 0936-5214

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-0028-1087956

Abstract

The first simple and efficient total synthesis of sporostatin has been accomplished in five steps starting from (S)-propylene oxide. The synthesis utilizes simple reactions such as esterification, cross-metathesis, and intramolecular Friedel-Crafts reaction as key steps.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Homoallyl Alcohol; Cross-metathesis; Intramolecular Friedel-crafts Reaction
ID Code:63182
Deposited On:28 Sep 2011 03:40
Last Modified:28 Sep 2011 03:40

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