Three-component reaction of a δ-hydroxy-α,β-unsaturated aldehyde with arylamines and 1,3-diketones: a novel synthesis of oxa-aza bicycles

Subba Reddy, Basi V. ; Divyavani, Ch. ; Begum, Zubeda ; Yadav, Jhillu S. (2010) Three-component reaction of a δ-hydroxy-α,β-unsaturated aldehyde with arylamines and 1,3-diketones: a novel synthesis of oxa-aza bicycles Synthesis, 2010 (10). pp. 1719-1723. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-0029-1218721

Abstract

δ-Hydroxy-α,β-unsaturated sugar aldehydes (Perlin aldehydes) undergo smooth coupling with β-enamino ketones and β-enamino esters generated in situ from arylamines and 1,3-dicarbonyl compounds in the presence of 10 mol% InCl3 in acetonitrile at 80°C, to produce oxa-aza-bicycles in good yields with high selectivity.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Perlin Aldehyde; 1,3-dicarbonyl Compounds; Indium Salts; Oxa-aza-bicycles
ID Code:63150
Deposited On:28 Sep 2011 03:44
Last Modified:28 Sep 2011 03:44

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