Pd(OAc)2-catalyzed C-H activation of indoles: a facile synthesis of 3-cyanoindoles

Subba Reddy, B. V. ; Begum, Zubeda ; Jayasudhan Reddy, Y. ; Yadav, J. S. (2010) Pd(OAc)2-catalyzed C-H activation of indoles: a facile synthesis of 3-cyanoindoles Tetrahedron Letters, 51 (25). pp. 3334-3336. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.04.086

Abstract

Indoles undergo smooth cyanation with CuCN in the presence of 20 mol % Pd(OAc)2 and 40 mol % CuBr2 in DMF to produce a wide range of the corresponding 3-cyanoindoles in good yields with high regioselectivity.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Indoles; Regioselective Cyanation; Pd(OAc)2; 3-Cyanoindoles; C-H Activation
ID Code:63147
Deposited On:28 Sep 2011 03:48
Last Modified:28 Sep 2011 03:48

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