Three-component one-pot synthesis of 3-(2-furanyl) indoles from acetylenedicarboxylate, isocyanide, and 3-formylindole

Subba Reddy, B. V. ; Mallikarjun Reddy, A. ; Somashekar, D. ; Yadav, J. S. ; Sridhar, B. (2010) Three-component one-pot synthesis of 3-(2-furanyl) indoles from acetylenedicarboxylate, isocyanide, and 3-formylindole Synthesis, 2010 (15). pp. 2571-2576. ISSN 0039-7881

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-0029-1218824

Abstract

The zwitterions derived from isocyanide and dimethyl acetylenedicarboxylate undergo smooth condensation with 3-formylindoles in benzene at room temperature to give the corresponding 3-(2-furanyl)indoles in good yields. This method provides a simple and convenient route to produce a wide range of 3-heteroarylindoles in a one-pot operation.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:3-formylindoles; Isocyanides; DMAD; Zwitterions; 3-furanylindoles
ID Code:63096
Deposited On:28 Sep 2011 03:44
Last Modified:28 Sep 2011 03:44

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