Indium(III) chloride catalyzed addition of indoles to activated aza-aromatic systems

Yadav, Jhillu S. ; Subba Reddy, Basi V. ; Vishnumurthy, Puttagari ; Premalatha, Kokku (2008) Indium(III) chloride catalyzed addition of indoles to activated aza-aromatic systems Synthesis, 2008 (5). pp. 719-724. ISSN 0039-7881

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-2008-1032175

Abstract

Addition of indoles and pyrroles to activated quinolines and isoquinolines is achieved using 10 mol% of indium(III) chloride as a catalyst to produce 2-(1H-indol-3-yl)-1,2-dihydroquinolines and 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines in excellent yields with high selectivity. This method is very useful for the functionalization of both indoles and quinolines in a one-pot operation.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Aza-aromatics; Indium Reagents; Indol-3-ylquinolines; Pyrrol-2-ylquinolines
ID Code:62957
Deposited On:24 Sep 2011 04:56
Last Modified:24 Sep 2011 04:56

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